Article
Molecular recognition in cytochrome P-450: mechanism for the control of uncoupling reactions.
Biochemistry - 2 Nov 1993
Loida P J, Sligar S G
Abstract excerpt
The pathway for utilization of pyridine nucleotide derived reducing equivalents in the cytochrome P-450 monooxygenase systems has three major branch points. The first is a partitioning between autoxidation of a ferrous, oxygenated heme adduct and input of the second reducing equivalent required for monooxygenase stoichiometry. The second is between dioxygen bond scission and release of two-electron-reduced O2 as...
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