Article
Neural cell adhesion molecule and prognosis of surgically resected lung cancer.
The American review of respiratory disease - 1 Oct 1993
Pujol J L, Simony J, Demoly P, Charpentier R, Laurent J C, Daurès J P, Lehmann M, Guyot V, Godard P, Michel F B
Abstract excerpt
The prognostic significance of the expression of neural cell adhesion molecule (NCAM), a neuroendocrine antigen in lung cancer, was analyzed by an indirect immunoperoxidase method in 97 surgically treated patients. Reactivity of MOC-1 and S-L 11.14, both cluster-1 monoclonal antibodies directed against NCAM, was positive in all nine small-cell lung cancers and in 16 of 88 (18%) non-small-cell lung cancers. For...
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