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Article

Correction of a lysosomal deficiency by contact-mediated enzyme transfer after bone marrow transplantation.

Transplantation - 1 Oct 1993

Bou-Gharios G, Adams G, Pace P, Warden P, Olsen I

Abstract excerpt

The effectiveness of bone marrow transplantation for treating lysosomal deficiency diseases relies on the ability of bone marrow cells to provide the missing enzyme to various tissues of the recipient. This has been shown to occur in vitro by endocytosis of enzyme secreted by bone marrow-derived...

Topics

Alleles
Animals
Bone Marrow Transplantation
Glucuronidase
Hair Color
Haplotypes
Leukocytes
Lymphocytes
Lysosomal Storage Diseases
Mice
Mice, Inbred C57BL
Mice, Mutant Strains

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Point Mutation

Source

Identifiers

PMID: 8212223
DOI: 10.1097/00007890-199310000-00040

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8212223-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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