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Enzyme replacement therapy for Gaucher disease

19 Nov 2008

Abstract excerpt

Gaucher disease is the most common lysosomal storage disease, and the first lysosomal storage disease for which a specific therapy has been developed. Enzyme replacement therapy, with glucocerebrosidase purified from human placentae, was introduced in 1991. Recombinant human glucocerebrosidase, produced by Chinese hamster ovary cells in tissue culture, became available in 1994 and has replaced the...

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PMID: 19063698
DOI: 10.1517/14712590802573395

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