Article
Increased trimipramine plasma levels during fluvoxamine comedication.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Mar 1994
Seifritz E, Holsboer-Trachsler E, Hemmeter U, Eap C B, Baumann P
Abstract excerpt
A depressive patient, a non-responder to trimipramine (TRI), was comedicated first with citalopram (CIT) and then with fluvoxamine (FLUV). Both the TRI-CIT and TRI-FLUV combination treatments led to a worsening of the depressive state and to the appearance of panic attacks. The addition of FLUV t...
Topics
- Aged
- Citalopram
- Depressive Disorder
- Dextromethorphan
- Drug Interactions
- Female
- Fluvoxamine
- Humans
- Mephenytoin
- Phenotype
- Trimipramine