Article
Phenotype and biological activity of neonatal equine chondrocytes cultured in a three-dimensional fibrin matrix.
American journal of veterinary research - 1 Mar 1994
Hendrickson D A, Nixon A J, Erb H N, Lust G
Abstract excerpt
Equine neonatal chondrocytes were cultured in three-dimensional fibrin matrices under conditions of immediate implantation or implantation following monolayer culture for 6 days, and 3 cell concentrations (1 x 10(5), 1 x 10(6), and 5 x 10(6) chondrocytes/cm3). Equine fibrinogen was collected by cryoprecipitation and polymerized by use of activated bovine thrombin. The fibrin implants were harvested and analyzed...
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