Article
Erosive rheumatoid factor negative and positive rheumatoid arthritis are immunogenetically similar.
The Journal of rheumatology - 1 Feb 1994
Vehe R K, Nepom G T, Wilske K R, Stage D, Begovich A B, Nepom B S
Abstract excerpt
OBJECTIVE: The relationship between rheumatoid factor positive (RF+) and rheumatoid factor negative (RF-) rheumatoid arthritis (RA) is controversial. We sought to determine whether the HLA genes conferring susceptibility for erosive RF+RA are also prevalent in patients with erosive RF-RA. METHODS: DNA-based HLA typing for DRB1, DQB1, and DPB1 was performed on 16 consistently RF--patients with erosive RA. RESULTS:...
Topics
- Adult
- Aged
- Alleles
- Arthritis, Rheumatoid
- Female
- Gene Frequency
- HLA-D Antigens
- HLA-DP Antigens
- HLA-DP beta-Chains
- HLA-DQ Antigens
- HLA-DQ beta-Chains