Mutation His322Asn in human acetylcholinesterase does not alter electrophoretic and catalytic properties of the erythrocyte enzyme.

Article

Mutation His322Asn in human acetylcholinesterase does not alter electrophoretic and catalytic properties of the erythrocyte enzyme.

Blood - 15 May 1994

Masson P, Froment M T, Sorenson R C, Bartels C F, Lockridge O

Abstract excerpt

The YT blood group antigen is located on human red blood cell (RBC) acetylcholinesterase. Wild-type acetylcholinesterase, YT1, has histidine at codon 322, whereas the genetic variant of acetylcholinesterase, YT2, has asparagine. This mutation is located within exon 2 of the ACHE gene, an exon tha...

Topics

Acetylcholinesterase
Electrophoresis
Erythrocytes
Histidine
Humans
Kinetics
Mutation
Structure-Activity Relationship

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