Article
Identification and regional localization of a highly polymorphic dinucleotide repeat D11S614 to the interval in 11q23.3 flanked by recurrent translocation breakpoints.
Annals of human genetics - 1 Oct 1993
Benham F, Sugiyama R, Hunt D, Gillett G, Smith M
Abstract excerpt
A highly informative dinucleotide repeat polymorphism has been identified at the D11S614 locus on chromosome 11q23. Ten different alleles have been observed at this locus, and the heterozygosity frequency is approximately 85%. Physical localization of this marker in a panel of somatic cell hybrids containing chromosome 11 translocations showed that it maps to 11q23.3, within the interval between the recurrent...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Female
- Gene Frequency
- Genetic Markers
- Humans
- Hybrid Cells
- Male
- Polymorphism, Genetic
- Repetitive Sequences, Nucleic Acid
