Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular basis for plasma alpha(1,3)-fucosyltransferase gene deficiency (FUT6).

The Journal of biological chemistry - 29 Apr 1994

Mollicone R, Reguigne I, Fletcher A, Aziz A, Rustam M, Weston B W, Kelly R J, Lowe J B, Oriol R

Abstract excerpt

While most humans express an alpha(1,3)-fucosyltransferase in plasma, 9% of individuals on the isle of Java (Indonesia) do not express this enzyme. Ninety-five percent of these plasma alpha(1,3)-fucosyltransferase-deficient individuals have Lewis negative phenotype on red cells, suggesting strong linkage disequilibrium between these two traits. To define the molecular basis for this plasma deficiency and to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pedigree
Share to Polymorphism, Genetic
Share to Alleles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Amino Acid Sequence

Share to Base Sequence

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 8175676

Genes

FUT6
FUT5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular basis for plasma alpha(1,3)-fucosyltransferase gene deficiency (FUT6).PMID 8175676Read ↗

Identification of two functionally deficient plasma alpha 3-fucosyltransferase (FUT6) alleles.Semantic proximity Read ↗

Molecular basis for Lewis alpha(1,3/1,4)-fucosyltransferase gene deficiency (FUT3) found in Lewis-negative Indonesian pedigrees.Semantic proximity Read ↗

A missense mutation in the FUT6 gene results in total absence of alpha3-fucosylation of human alpha1-acid glycoprotein.Semantic proximity Read ↗

Allelic diversity of the human plasma alpha(1,3)fucosyltransferase gene (FUT6).Semantic proximity Read ↗

Identification of a new plasma alpha(1,3)fucosyltransferase (FUT6) allele requires an extended genotyping strategy.Semantic proximity Read ↗

Influence of Lewis alpha1-3/4-L-fucosyltransferase (FUT3) gene mutations on enzyme activity, erythrocyte phenotyping, and circulating tumor marker sialyl-Lewis a levels.Semantic proximity Read ↗

Identification of 14 new alleles at the fucosyltransferase 1, 2, and 3 loci in Styrian blood donors, Austria.Semantic proximity Read ↗

Significance of each of three missense mutations, G484A, G667A, and G808A, present in an inactive allele of the human Lewis gene (FUT3) for alpha(1,3/1,4)fucosyltransferase inactivation.Semantic proximity Read ↗

Molecular analysis of plasma alpha 1,3-fucosyltransferase deficiency and development of the methods for its genotyping.Semantic proximity Read ↗

Molecular analysis of secretor type α(1,2)‐fucosyltransferase gene mutations in the Chinese and Thai populationsSemantic proximity Read ↗

Contrasting patterns of polymorphisms at the ABO-secretor gene (FUT2) and plasma alpha(1,3)fucosyltransferase gene (FUT6) in human populations.Semantic proximity Read ↗

Systematic sequence analysis of the human fucosyltransferase 2 (FUT2) gene identifies novel sequence variations and alleles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.