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Article

Six mutations in the glucokinase gene identified in MODY by using a nonradioactive sensitive screening technique.

Diabetes - 1 May 1994

Hager J, Blanché H, Sun F, Vaxillaire N V, Poller W, Cohen D, Czernichow P, Velho G, Robert J J, Cohen N

Abstract excerpt

We have reported that 56% of French families with maturity-onset diabetes of the young (MODY) carry a mutation in the glucokinase gene (GCK). Therefore, we have established a quick and sensitive nonradioactive technique (with the PhastSystem based on single-strand conformation polymorphism [SSCP] analysis) to routinely screen the 12 exons of GCK for mutations. We have studied GCK in 12 young hyperglycemic...

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Source

Identifiers

PMID: 8168652
DOI: 10.2337/diab.43.5.730

Genes

GCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Six mutations in the glucokinase gene identified in MODY by using a nonradioactive sensitive screening technique.PMID 8168652Read ↗

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Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes.Semantic proximity Read ↗

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