Cultured skin fibroblasts derived from three patients with disseminated superficial actinic porokeratosis (DSAP) are hypersensitive to the lethal effects of X-radiation but not to those of ultraviolet (UV) light.

doi:10.1111/j.1600-0625.1993.tb00029.x

Article

Cultured skin fibroblasts derived from three patients with disseminated superficial actinic porokeratosis (DSAP) are hypersensitive to the lethal effects of X-radiation but not to those of ultraviolet (UV) light.

Experimental dermatology - 1 Aug 1993

Watanabe R, Otsuka F

Abstract excerpt

Disseminated superficial actinic porokeratosis (DSAP), skin lesions of which are known to be induced by ultraviolet (UV) light, does not develop into skin cancer as frequently as other types of porokeratosis (PK). To establish the cellular basis of this characteristic of DSAP, we examined the col...

Topics

Aged
Cell Death
Cells, Cultured
Female
Fibroblasts
Genetic Predisposition to Disease
Humans
Male
Middle Aged
Porokeratosis
Radiation Tolerance
Skin Neoplasms

Cultured skin fibroblasts derived from three patients with disseminated superficial actinic porokeratosis (DSAP) are hypersensitive to the lethal effects of X-radiation but not to those of ultraviolet (UV) light.

Abstract excerpt

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