Prediction of bone density from vitamin D receptor alleles.

doi:10.1038/367284a0

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Article

Prediction of bone density from vitamin D receptor alleles.

Nature - 20 Jan 1994

Morrison N A, Qi J C, Tokita A, Kelly P J, Crofts L, Nguyen T V, Sambrook P N, Eisman J A

Abstract excerpt

Bone density achieved in early adulthood is the major determinant of risk of osteoporotic fracture. Up to 60% of women suffer osteoporotic fractures as a result of low bone density, which is under strong genetic control acting through effects on bone turnover. Here we show that common allelic var...

Topics

Adolescent
Adult
Aged
Alleles
Analysis of Variance
Base Sequence
Bone Density
DNA Primers
Female
Genotype
Humans
Male
Menopause
Middle Aged
Molecular Sequence Data
Receptors, Calcitriol
Spine
Twins

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