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Polymerase Chain Reaction-Based Diagnosis of Onchocerca volvulus Infection: Improved Detection of Patients with Onchocerciasis

1 Mar 1994

Abstract excerpt

Definitive diagnosis of Onchocerca volvulus (Ov) infection requires the identification of the parasite in either the skin or subcutaneous nodules. These parasitologic approaches suffer from poor sensitivity. To assess the efficacy and utility of a polymerase chain reaction (PCR)-based diagnosis for Ov infection, skin snips were examined from 94 persons in an Ov-endemic region of Ecuador, and results were compared...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8158053
DOI: 10.1093/infdis/169.3.686

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