Fertilization and early embryology: Fertilization potential in vitro is correlated with head-specific mannose — ligand receptor expression, acrosome status and membrane cholesterol content*

Abstract excerpt

Normozoospermic men who do not fertilize human eggs in vitro constitute a clearly identifiable class of occult male factor infertility. We have studied the relationships between in-vitro fertilization (IVF) outcomes and the appearance of sperm surface mannose lectin/zona pellucida ligand activity measured by the binding of fluorescein isothiocyanate (FITC)-labelled mannosylated albumin. Of 338 semen specimens...

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