Article
Evidence for autosomal dominant transmission in Tourette's syndrome. United Kingdom cohort study.
The British journal of psychiatry : the journal of mental science - 1 May 1993
Eapen V, Pauls D L, Robertson M M
Abstract excerpt
Complex segregation analyses were performed on families ascertained through 40 unselected consecutive patients with Tourette's syndrome to examine the hypothesis that its transmission is consistent with genetic inheritance. Analyses were done using several diagnostic classifications. All results were consistent with an autosomal dominant gene with high penetrance. The penetrances ranged from 0.882 to 1.000 for...
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