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Article

Human glucose-6-phosphate dehydrogenase: structure and function of normal and variant enzymes.

Haematologia - 1 Jan 1993

Hirono A, Miwa S

Abstract excerpt

Glucose-6-phosphate dehydrogenase (G6PD) is a unique enzyme with many genetic variants. Recent progress in molecular biological techniques have provided several important findings about the structure-function relationship of human G6PD. A putative substrate glucose-6-phosphate binding (around Lys 205) and a putative 'structural' NADP binding site (around Lys 386) have been identified. A conservative segment...

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PMID: 8244203

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