Interferon (IFN)-alpha 2 genotype analysis of Chinese chronic hepatitis B patients undergoing recombinant IFN-alpha 2a therapy.

doi:10.1093/infdis/169.4.875

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Article

Interferon (IFN)-alpha 2 genotype analysis of Chinese chronic hepatitis B patients undergoing recombinant IFN-alpha 2a therapy.

The Journal of infectious diseases - 1 Apr 1994

Crowe J S, Gewert D R, Barber K A, Lewis A P, Sims M J, Davies S L, Salom C L, Wood J, Thomas H C, Thursz M

Abstract excerpt

Sixteen Chinese chronic hepatitis B virus (HBV)-infected patients were treated with recombinant interferon-alpha 2a (rIFN-alpha 2a). Of these, 8 made a response to IFN, with titers of neutralizing antibody of 141-4525 as determined by an antiviral neutralization bioassay. To determine whether the...

Topics

Adult
Amino Acid Sequence
Antibodies
Antibody Formation
Asian People
Base Sequence
China
Chronic Disease
Cloning, Molecular
DNA
DNA Primers
Female
Genotype
Hepatitis B
Humans
Interferon alpha-2
Interferon-alpha
Male

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Open in PubMed

Identifiers

PMID: 8133104
DOI: 10.1093/infdis/169.4.875

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8133104-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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