Usefulness of simple assays for serum concentration of hepatitis C virus RNA and HCV genotype in predicting the response of patients with chronic hepatitis C to interferon alpha 2a therapy.

doi:10.1002/jmv.1890460215

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Article

Usefulness of simple assays for serum concentration of hepatitis C virus RNA and HCV genotype in predicting the response of patients with chronic hepatitis C to interferon alpha 2a therapy.

Journal of medical virology - 1 Jun 1995

Suzuki T, Tanaka E, Matsumoto A, Urushihara A, Sodeyama T

Abstract excerpt

The use of two new assays was evaluated for predicting the response to interferon (IFN) therapy in patients with chronic hepatitis C. The genotype of hepatitis C virus (HCV) was established by an enzyme-linked immunosorbent assay based on genotype-specific recombinant peptides of the NS4 region (genotyping ELISA). The concentration of HCV RNA was measured by a branched DNA assay (bDNA assay). Seventy-eight...

Topics

Adult
Aged
Alanine Transaminase
Chronic Disease
Enzyme-Linked Immunosorbent Assay
Female
Follow-Up Studies
Genotype
Hepacivirus
Hepatitis C
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interferon Type I

Interferon alpha-2

Interferon-alpha

Male

Middle Aged

Polymerase Chain Reaction

RNA, Viral

Source

Open in PubMed

Identifiers

PMID: 7636506
DOI: 10.1002/jmv.1890460215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7636506-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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