Simultaneous characterization of in vitro growing cells by fluorescence in situ hybridization (FISH) and Ki-67 labeling.

Abstract excerpt

Because cytogenetic analysis and fluorescence in situ hybridization (FISH) techniques fail to provide information about the immunological phenotype with respect to differentiation and malignancy of in vitro growing cells, we developed a system which combines immunophenotyping and FISH. Using immunological detection of the proliferation fraction in short term human cell cultures from different origins by Ki-67...

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