Article
Lymphocyte function in autism and Rett syndrome.
Neuropsychobiology - 1 Jan 1994
Plioplys A V, Greaves A, Kazemi K, Silverman E
Abstract excerpt
Peripheral blood lymphocytes from 17 patients with autism were separated on a Ficoll-Hypaque density gradient. Patients had normal numbers of T and B cells and T cell subsets. Although CD4:CD8 ratios were normal for the whole group (2.09 +/- 0.97), 6 patients had elevated ratios (> 2.2) and 5 had decreased ratios (< 1.5). Mitogen-induced proliferation (concanavalin-A and phytohemagglutinin) was normal as was the...
Topics
- Adolescent
- Adult
- Antigens, Surface
- Autistic Disorder
- B-Lymphocytes
- CD4-CD8 Ratio
- Cell Division
- Child
- Female
- Humans
- Lymphocyte Activation
- Lymphocytes