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Article

Multimeric structure of ClC-1 chloride channel revealed by mutations in dominant myotonia congenita (Thomsen).

The EMBO journal - 15 Feb 1994

Steinmeyer K, Lorenz C, Pusch M, Koch M C, Jentsch T J

Abstract excerpt

Voltage-gated ClC chloride channels play important roles in cell volume regulation, control of muscle excitability, and probably transepithelial transport. ClC channels can be functionally expressed without other subunits, but it is unknown whether they function as monomers. We now exploit the properties of human mutations in the muscle chloride channel, ClC-1, to explore its multimeric structure. This is based...

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Identifiers

PMID: 8112288
DOI: 10.1002/j.1460-2075.1994.tb06315.x
PMCID: PMC394869

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Multimeric structure of ClC-1 chloride channel revealed by mutations in dominant myotonia congenita (Thomsen).PMID 8112288Read ↗

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