Article
Molecular analysis of herpes simplex virus type 1 during epinephrine-induced reactivation of latently infected rabbits in vivo.
Journal of virology - 1 Mar 1994
Bloom D C, Devi-Rao G B, Hill J M, Stevens J G, Wagner E K
Abstract excerpt
Infectious virus assays and PCR amplification of DNA and RNA were used to investigate herpes simplex virus (HSV) DNA replication and gene expression in the rabbit corneal model for virus reactivation in vivo. We used carefully defined latency-associated transcript-negative (LAT-) and LAT+ promote...
Topics
- Animals
- Base Sequence
- Capsid
- Capsid Proteins
- Cornea
- Epinephrine
- Herpes Simplex
- Herpesvirus 1, Human
- In Situ Hybridization
- Molecular Sequence Data
- Mutation
- Neurons
- RNA, Messenger
- RNA, Viral
- Rabbits
- Transcription, Genetic
- Trigeminal Ganglion
- Virus Activation
