Article
Wolfram syndrome: a mitochondrial-mediated disorder?
Lancet (London, England) - 4 Sept 1993
Bu X, Rotter J I
Abstract excerpt
Mitochondrial DNA mutations cause several human diseases, (eg, Leber's hereditary optic neuropathy). Wolfram syndrome (characterised by diabetes insipidus, diabetes mellitus, optic atrophy, and deafness) also has, in some cases, a mitochondrial origin. The disease, often familial, has been well d...
Topics
- DNA, Mitochondrial
- Genome
- Humans
- Models, Genetic
- Mutation
- Phenotype
- Wolfram Syndrome