Article
Familial Mediterranean fever (FMF) in Moroccan Jews: demonstration of a founder effect by extended haplotype analysis.
American journal of human genetics - 1 Sept 1993
Aksentijevich I, Pras E, Gruberg L, Shen Y, Holman K, Helling S, Prosen L, Sutherland G R, Richards R I, Dean M
Abstract excerpt
Familial Mediterranean fever (FMF) is an autosomal recessive disease causing attacks of fever and serositis. The FMF gene (designated "MEF") is on 16p, with the gene order 16cen-D16S80-MEF-D16S94-D16S283-D16S291-++ +16pter. Here we report the association of FMF susceptibility with alleles as D16S...
Topics
- Alleles
- Chi-Square Distribution
- Chromosomes, Human, Pair 16
- Familial Mediterranean Fever
- Female
- Gene Frequency
- Genes, Recessive
- Genetic Markers
- Haplotypes
- Humans
- Israel
- Jews
- Linkage Disequilibrium
- Male