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Article

A restriction fragment length polymorphism results in a nonconservative amino acid substitution encoded within the first exon of the human lysyl oxidase gene.

Genomics - 1 May 1993

Csiszar K, Mariani T J, Gosin J S, Deak S B, Boyd C D

Abstract excerpt

A cDNA covering most of the coding sequence for human lysyl oxidase was used to screen, by Southern blot analysis, genomic DNA from circulating lymphocytes obtained from unrelated, apparently normal individuals. A heritable restriction fragment length polymorphism (RFLP) within a PstI restriction site was detected in 36% of individuals screened (a total of 72 chromosomes were analyzed). The major allele was...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Consensus Sequence
DNA
DNA, Recombinant
Exons
Humans
Lymphocytes
Molecular Sequence Data
Polymorphism, Restriction Fragment Length

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein-Lysine 6-Oxidase

Source

Identifiers

PMID: 8100215
DOI: 10.1006/geno.1993.1203

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8100215-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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