DNA polymorphisms in the lactase gene. Linkage disequilibrium across the 70-kb region.

doi:10.1159/000472271

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Article

DNA polymorphisms in the lactase gene. Linkage disequilibrium across the 70-kb region.

European journal of human genetics : EJHG - 1 Jan 1995

Harvey C B, Pratt W S, Islam I, Whitehouse D B, Swallow D M

Abstract excerpt

The enzyme lactase, which is responsible for the digestion of dietary lactose, is present in the intestine of some adults but not others. As a means of providing a platform to explore the molecular basis of this nutritionally relevant genetic variation we have screened for polymorphism in several regions of the lactase gene. In each case simple polymerase chain reaction-based procedures (including single-strand...

Topics

Alleles
Base Sequence
Electrophoresis, Polyacrylamide Gel
France
Haplotypes
Humans
Lactase
Linkage Disequilibrium
Molecular Sequence Data
Pedigree
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Polymorphism, Single-Stranded Conformational

Utah

beta-Galactosidase

Source

Open in PubMed

Identifiers

PMID: 7767654
DOI: 10.1159/000472271

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7767654-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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