The intriguing link between modulation of both multidrug resistance and ligand-toxin conjugate cytotoxicity.

doi:10.1016/0014-5793(93)81337-y

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Article

The intriguing link between modulation of both multidrug resistance and ligand-toxin conjugate cytotoxicity.

FEBS letters - 1 Jun 1993

Jaffrézou J P, Laurent G

Abstract excerpt

Pharmacological agents which possess a chemosensitizing activity (i.e. the ability to modulate the multidrug resistance phenotype) can equally enhance ligand-toxin conjugate cytotoxicity. By confronting results obtained in both fields of research it appears that quite a number of agents, which ar...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Animals
Carrier Proteins
Cell Survival
Drug Resistance
Immunotoxins
Ligands
Membrane Glycoproteins
Models, Biological
Phenotype
Toxins, Biological

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