Article
The intriguing link between modulation of both multidrug resistance and ligand-toxin conjugate cytotoxicity.
FEBS letters - 1 Jun 1993
Jaffrézou J P, Laurent G
Abstract excerpt
Pharmacological agents which possess a chemosensitizing activity (i.e. the ability to modulate the multidrug resistance phenotype) can equally enhance ligand-toxin conjugate cytotoxicity. By confronting results obtained in both fields of research it appears that quite a number of agents, which are structurally unrelated, possess this bilateral effect. We have therefore attempted to provide a brief review of the...
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