Article
A novel multicopy suppressor of a groEL mutation includes two nested open reading frames transcribed from different promoters.
The EMBO journal - 1 Mar 1993
Greener T, Govezensky D, Zamir A
Abstract excerpt
When present on a multicopy plasmid, a newly discovered gene (sugE) mapping to 94 min on the Escherichia coli chromosome, suppresses a groEL mutation and mimics the effects of groE overexpression. A groEL mutant of E.coli, transformed with the Klebsiella pneumoniae nif gene cluster, failed to accumulate nitrogenase components [Govezensky et al. (1991) J. Bacteriol., 173, 6339-6346]. Transformation with sugE...
Topics
- Amino Acid Sequence
- Bacterial Proteins
- Base Sequence
- Chaperonin 60
- Chromosomes, Bacterial
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Genes, Suppressor