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High Levels of HIV-1 in Plasma During All Stages of Infection Determined By Competitive PCR

19 Mar 1993

Abstract excerpt

Quantitative competitive polymerase chain reaction (QC-PCR) methods were used to quantify virion-associated human immunodeficiency virus type-1 (HIV-1) RNA in plasma from 66 patients with Centers for Disease Control stage I to IVC1 infection. HIV-1 RNA, ranging from 100 to nearly 22,000,000 copies per milliliter of plasma (corresponding to 50 to 11,000,000 virions per milliliter), was readily quantified in all...

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PMID: 8096089
DOI: 10.1126/science.8096089

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