Article
HLA-DR and HLA-DP genotypes and immunoglobulin E responses to common major allergens.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 May 1994
Young R P, Dekker J W, Wordsworth B P, Schou C, Pile K D, Matthiesen F, Rosenberg W M, Bell J I, Hopkin J M, Cookson W O
Abstract excerpt
In order to test for human histocompatibility leucocyte antigens (HLA) class II restriction of IgE responses, 431 subjects from 83 families were genotyped at the HLA-DR and HLA-DP loci and serotyped for IgE responses to six major allergens from common aero-allergen sources. A possible excess of H...
Topics
- Alleles
- Allergens
- Gene Frequency
- Genetic Linkage
- Genotype
- HLA-DP Antigens
- HLA-DR Antigens
- Humans
- Hypersensitivity
- Immunoglobulin E
- Polymerase Chain Reaction