Article
Molecular basis of beta-thalassemia minor in Taiwan.
International journal of hematology - 1 Jun 1994
Chang J G, Lin C P, Liu T C, Chiou S S, Chen P H, Lee L S, Chen T P
Abstract excerpt
The mutations producing beta-thalassemia minor in 227 Taiwanese were studied using the method of naturally and amplified created restriction sites. beta-Thalassemia minor was caused by one beta-globin gene mutation in most of the cases (225/227); only a few cases were caused by two gene mutation (2/227). The most common type of mutation was frameshift codon 41/42 (-TCTT) (93/227), followed in descending order by...
Topics
- Adolescent
- Adult
- Aged
- Base Sequence
- Globins
- Humans
- Middle Aged
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Taiwan
- beta-Thalassemia