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Article

Developmental Expression of Nicein Adhesion Protein (Laminin-5) Subunits Suggests Multiple Morphogenic Roles

1 Jan 1994

Abstract excerpt

Nicein/kalinin (laminin-5) is a heterotrimeric laminin-like adhesion protein, which is secreted at the basement membrane of subsets of epithelia and is involved in the etiology of junctional epidermolysis bullosa, a severe human blistering disease characterized by disadhesion of epidermis from dermis. cDNA clones encoding the three chains of mouse nicein and antibodies specific to each polypeptide were used to...

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PMID: 8081888
DOI: 10.3109/15419069409004431

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