Origin of transferable cefotaxime resistance in a clinical isolate of Escherichia coli by mutation.

Abstract excerpt

A clinical isolate of Escherichia coli susceptible to cefotaxime and ceftazidime from a polytraumatic pediatric patient, transferred a series of determinants of resistance to antibiotics, including cephalotin-cefazolin, to a recipient strain of E. coli K-12. When cephalotin-resistant clones of K-12 were tested for their resistance to cefotaxime on solid media with this antibiotic, nine clones could be isolated...

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