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Article

E5a gene of human papillomavirus type 11 is required for initiation but not for maintenance of transformation in NIH 3T3 cells.

The Journal of general virology - 1 Aug 1994

Chen S L, Tsao Y P, Lee J W, Liu H S, Yang C M, Tsao L T

Abstract excerpt

We have previously shown that the E5a gene of human papilloma virus type 11 (HPV-11/HPV-6c) is a transforming oncogene. In order to dissect the biological consequences of E5a gene expression we utilized the lac operator/repressor system to manipulate E5a gene expression. Cells were cotransfected with the lac repressor gene and the E5a gene that had been inserted downstream of a simian virus 40 (SV40) promoter...

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Identifiers

PMID: 8046397
DOI: 10.1099/0022-1317-75-8-1953

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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