Article
Involvement of serine 74 in the enzyme-coenzyme interaction of rat liver mitochondrial aldehyde dehydrogenase.
Biochemistry - 2 Aug 1994
Rout U K, Weiner H
Abstract excerpt
It has been suggested that the active site nucleophile in sheep liver aldehyde dehydrogenase was not a cysteine residue but was a serine located at position 74 [Loomes, K. M., Midwinter, G. G., Blackwell, L. F., & Buckley, P. D. (1990) Biochemistry 29, 2070-2080]. This enzyme form has not yet bee...
Topics
- Adenosine Diphosphate Ribose
- Aldehyde Dehydrogenase
- Animals
- Coenzymes
- Enzyme Stability
- Esterases
- Kinetics
- Mitochondria, Liver
- Mutation
- NAD
- Rats
- Recombinant Proteins
- Sepharose
- Serine
- Substrate Specificity