Complete association of the HLA-DRB1*04 and -DQB1*04 alleles with Vogt-Koyanagi-Harada's disease.

doi:10.1016/0198-8859(94)90257-7

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Article

Complete association of the HLA-DRB104 and -DQB104 alleles with Vogt-Koyanagi-Harada's disease.

Human immunology - 1 Mar 1994

Shindo Y, Ohno S, Yamamoto T, Nakamura S, Inoko H

Abstract excerpt

VKH disease is a bilateral panuveitis and has been known to be closely associated with the particular HLA class II antigens HLA-DR4 and -DQ4, defined by serologic typing. In this study, 63 Japanese VKH patients were analyzed for HLA class II alleles at the DNA level using the PCR-RFLP method. The...

Topics

Adult
Aged
Alleles
Amino Acid Sequence
Female
Gene Frequency
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DRB1 Chains
Histocompatibility Antigens Class II
Humans
Japan
Male
Middle Aged
Molecular Sequence Data
Polymerase Chain Reaction

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Open in PubMed

Identifiers

PMID: 8026985
DOI: 10.1016/0198-8859(94)90257-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8026985-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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