Article
Influence of HLA-DRB1 gene variation on the clinical course of Vogt-Koyanagi-Harada disease.
Investigative ophthalmology & visual science - 1 Feb 1994
Islam S M, Numaga J, Matsuki K, Fujino Y, Maeda H, Masuda K
Abstract excerpt
PURPOSE: To investigate the difference, if any, in the immunogenetic backgrounds between two clinical subtypes of Vogt-Koyanagi-Harada disease (VKH). METHODS: HLA-DR4 gene variations were investigated in 46 Japanese patients, 28 with the prolonged type and 18 with the nonprolonged type of VKH. HL...
Topics
- Base Sequence
- DNA Primers
- Electrophoresis, Polyacrylamide Gel
- Female
- Gene Frequency
- Genes, MHC Class II
- Genetic Variation
- HLA-DR Antigens
- HLA-DR4 Antigen
- HLA-DRB1 Chains
- Histocompatibility Antigens Class II
- Humans
- Male
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Random Allocation
- Uveomeningoencephalitic Syndrome