Article
HLA-DRB1*0405 is the predominant allele in Brazilian patients with Vogt-Koyanagi-Harada disease.
Human immunology - 1 Mar 1998
Goldberg A C, Yamamoto J H, Chiarella J M, Marin M L, Sibinelli M, Neufeld R, Hirata C E, Olivalves E, Kalil J
Abstract excerpt
Vogt-Koyanagi-Harada (VKH) disease is a rare disorder affecting pigmented structures especially the eye and is the main cause of autoimmune non-infectious uveitis in the Brazilian population. The autoimmune target is believed to be the melanocyte. A strong association of VKH disease with HLA-DR4 in the Japanese population is well known. The same association, albeit with lower relative risks has been found in...
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