HLA-DRB1*0405 is the predominant allele in Brazilian patients with Vogt-Koyanagi-Harada disease.

doi:10.1016/s0198-8859(97)00265-6

Back to search

Article

HLA-DRB1*0405 is the predominant allele in Brazilian patients with Vogt-Koyanagi-Harada disease.

Human immunology - 1 Mar 1998

Goldberg A C, Yamamoto J H, Chiarella J M, Marin M L, Sibinelli M, Neufeld R, Hirata C E, Olivalves E, Kalil J

Abstract excerpt

Vogt-Koyanagi-Harada (VKH) disease is a rare disorder affecting pigmented structures especially the eye and is the main cause of autoimmune non-infectious uveitis in the Brazilian population. The autoimmune target is believed to be the melanocyte. A strong association of VKH disease with HLA-DR4...

Topics

Adolescent
Adult
Alleles
Brazil
Child
Female
HLA-DR Antigens
HLA-DRB1 Chains
Histocompatibility Testing
Humans
Male
Middle Aged
Uveomeningoencephalitic Syndrome

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.