Article
Re-evaluation of gonadotropin-releasing hormone (GnRH) action on pituitary cell differentiation with special regard to its effect on LH and TSH cell types.
Journal of neuroendocrinology - 1 Feb 1994
Héritier A G, Dubois P M
Abstract excerpt
We have previously demonstrated that TRH induces several hypophyseal cell type differentiation. In the present study, we re-evaluated the effect of GnRH on gonadotroph differentiation, and we determined whether gonadotropin is implicated in the appearance of other pituitary cell types. These effects were compared to the influence of TRH on LH and TSH cell differentiation. Pituitary primordia of 11 day-old rat...
Topics
- Animals
- Cell Differentiation
- Culture Media
- Female
- Gonadotropin-Releasing Hormone
- Immunohistochemistry
- Luteinizing Hormone
- Organ Culture Techniques
- Phenotype
- Pituitary Gland
- Pregnancy
