Isolation and analysis of novel human melanocyte-specific cDNA clones.

doi:10.1089/dna.1994.13.515

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Article

Isolation and analysis of novel human melanocyte-specific cDNA clones.

DNA and cell biology - 1 May 1994

Gratas C, Herlyn M, Becker D

Abstract excerpt

Human melanoma represents a neurocrest-derived malignancy, occurring in 10% of cases within the setting of a familial predisposition and in 90% of cases with sporadic onset. It is estimated that more than 85% of familial melanomas and about 40% of sporadic melanomas arise from melanocytic precurs...

Topics

Cells, Cultured
Chromosome Mapping
DNA, Complementary
Genetic Predisposition to Disease
Humans
Melanocytes
Melanoma
Polymerase Chain Reaction
Sequence Analysis, DNA
Tumor Cells, Cultured

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