Isolation and analysis of novel human melanocyte-specific cDNA clones.

Abstract excerpt

Human melanoma represents a neurocrest-derived malignancy, occurring in 10% of cases within the setting of a familial predisposition and in 90% of cases with sporadic onset. It is estimated that more than 85% of familial melanomas and about 40% of sporadic melanomas arise from melanocytic precursor lesions. In an attempt to isolate genes that may play a role in human melanocytic progression, we applied...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Polymerase Chain Reaction
• Share to Cells, Cultured
• Share to Chromosome Mapping