HLA and disease associations: detecting the strongest association.

doi:10.1111/j.1399-0039.1994.tb02291.x

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Article

HLA and disease associations: detecting the strongest association.

Tissue antigens - 1 Jan 1994

Svejgaard A, Ryder L P

Abstract excerpt

A major aim of HLA and disease association studies is to identify the causative HLA factor truly responsible for the association. This is usually difficult due to the pronounced linkage disequilibrium between most HLA determinants. The causative factor must show the strongest association compared to all other factors. Here we describe a simple analysis which can be used to identify which of two factors, say A and...

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