Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.

5 Jul 1994

Abstract excerpt

Production of the glycoprotein hormone erythropoietin (Epo) in response to hypoxic stimuli is almost entirely restricted to particular cells within liver and kidney, yet the transcriptional enhancer lying 3' to the Epo gene shows activity inducible by hypoxia after transfection into a wide variety of cultured cells. The implication of this finding is that many cells which do not produce Epo contain a similar, if...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Erythrocyte Function and Pathophysiology
Share to Erythropoietin and Anemia Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8022811
DOI: 10.1073/pnas.91.14.6496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer.PMID 8022811Read ↗

Regulation of the erythropoietin geneSemantic proximity Read ↗

A Nuclear Factor Induced by Hypoxia via De Novo Protein Synthesis Binds to the Human Erythropoietin Gene Enhancer at a Site Required for Transcriptional ActivationSemantic proximity Read ↗

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.Semantic proximity Read ↗

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia.Semantic proximity Read ↗

Enhancer element at the 3'-flanking region controls transcriptional response to hypoxia in the human erythropoietin geneSemantic proximity Read ↗

A 24-base-pair sequence 3' to the human erythropoietin gene contains a hypoxia-responsive transcriptional enhancer.Semantic proximity Read ↗

Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene.Semantic proximity Read ↗

Human erythropoietin gene expression in transgenic mice: multiple transcription initiation sites and cis-acting regulatory elements.Semantic proximity Read ↗

Glucose catabolism in cancer cells: identification and characterization of a marked activation response of the type II hexokinase gene to hypoxic conditions.Semantic proximity Read ↗

Cell-type-specific and hypoxia-inducible expression of the human erythropoietin gene in transgenic mice.Semantic proximity Read ↗

Induction of Phosphoglycerate Kinase 1 Gene Expression by HypoxiaSemantic proximity Read ↗

Identification of a placental-specific enhancer in the rat placental lactogen II gene that contains binding sites for members of the Ets and AP-1 (activator protein 1) families of transcription factors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.