Article
Transposon-induced pigment-deficient mutants of Porphyromonas gingivalis.
FEMS microbiology letters - 15 Nov 1994
Hoover C I, Yoshimura F
Abstract excerpt
Trypsin-like protease activity, hemagglutination activity, and accumulation of heme-containing compounds (black pigment) are considered to be virulence factors of Porphyromonas gingivalis. Transposon-mutagenesis was used for the first time to isolate pigment-deficient mutants. These mutants exhibited simultaneous deficiency in trypsin-like protease activity and hemagglutination activity. Two major...
Topics
- Bacterial Proteins
- Cell Membrane
- Conjugation, Genetic
- DNA Transposable Elements
- Hemagglutinins
- Heme
- Mutagenesis, Site-Directed
- Phenotype
- Porphyromonas gingivalis
- Trypsin
- Virulence
