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Article

Human endothelial cells are defective in diabetic vascular disease.

The Journal of surgical research - 1 Dec 1994

Sank A, Wei D, Reid J, Ertl D, Nimni M, Weaver F, Yellin A, Tuan T L

Abstract excerpt

Diabetic vascular disease is characterized pathologically by endothelial cell (EC) hyperplasia and basement membrane (BM) thickening. One key question regarding the pathogenesis of diabetic vascular disease is whether the EC or BM or both are primarily defective and responsible for these pathological changes. Previous studies, which took the approach of creating artificial diabetic conditions, have been...

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Identifiers

PMID: 7996840
DOI: 10.1006/jsre.1994.1195

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