Article
[Susceptibility genes in immune-mediated neurological diseases].
Nihon rinsho. Japanese journal of clinical medicine - 1 Nov 1994
Nishizawa M
Abstract excerpt
Antigen presenting cells can express on the surface proteolytic fragments of antigens, which are bound to peptide-binding grooves formed by the heterodimeric MHC class II molecules. The grooves consist of highly polymorphic amino acid residues, determining affinity between antigenic peptides and...
Topics
- Animals
- Genes, MHC Class II
- Genetic Predisposition to Disease
- Immune System Diseases
- Nervous System Diseases
- T-Lymphocytes
