Article
Lipopolysaccharide and splenic tumoricidal macrophage activation.
Journal of leukocyte biology - 1 Dec 1994
Verstovsek S, Zaleskis G, Maccubbin D L, Mihich E, Ehrke M J
Abstract excerpt
Splenic macrophage tumoricidal activity was examined and a splenic macrophage tumoricidal assay was established. Initially, mixtures of lipopolysaccharide (LPS) and spleen single cell suspensions (SSCS) were cultured for 1-4 days. Adherent macrophages, washed free of nonadherent cells and LPS, were then examined and were found to lack tumoricidal activity in a standard 18-h 51Cr release assay. However,...
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