Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog.

doi:10.1126/science.7992058

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Article

Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog.

Science (New York, N.Y.) - 9 Dec 1994

Liu H, Köhler J, Fink G R

Abstract excerpt

A Candida albicans gene (CPH1) was cloned that encodes a protein homologous to Saccharomyces cerevisiae Ste12p, a transcription factor that is the target of the pheromone response mitogen-activated protein kinase cascade. CPH1 complements both the mating defect of ste12 haploids and the filamento...

Topics

Amino Acid Sequence
Base Sequence
Candida albicans
Cloning, Molecular
Culture Media
Fungal Proteins
Genes, Fungal
Genetic Complementation Test
Molecular Sequence Data
Mutation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Transcription Factors

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