Article
Suppression of hyphal formation in Candida albicans by mutation of a STE12 homolog.
Science (New York, N.Y.) - 9 Dec 1994
Liu H, Köhler J, Fink G R
Abstract excerpt
A Candida albicans gene (CPH1) was cloned that encodes a protein homologous to Saccharomyces cerevisiae Ste12p, a transcription factor that is the target of the pheromone response mitogen-activated protein kinase cascade. CPH1 complements both the mating defect of ste12 haploids and the filamentous growth defect of ste12/ste12 diploids. Candida albicans strains without a functional CPH1 gene (cph1/cph1) show...
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