Article
Birth after preimplantation diagnosis of the cystic fibrosis delta F508 mutation by polymerase chain reaction in human embryos resulting from intracytoplasmic sperm injection with epididymal sperm.
JAMA - 21 Dec 1994
Liu J, Lissens W, Silber S J, Devroey P, Liebaers I, Van Steirteghem A
Abstract excerpt
Men with congenital bilateral absence of the vas deferens (CBAVD) have been regarded as presenting a mild form of cystic fibrosis (CF). In this article, we report a case of male-factor infertility, in which both partners are carriers of the delta F508 mutation and the male partner has CBAVD. Micr...
Topics
- Adult
- Cystic Fibrosis
- Embryo, Mammalian
- Epididymis
- Female
- Fertilization in Vitro
- Humans
- Infant, Newborn
- Insemination, Artificial, Homologous
- Male
- Microsurgery
- Mutation
- Polymerase Chain Reaction
- Prenatal Diagnosis
- Spermatozoa
- Suction
- Vas Deferens