Article
[Severe male infertility. Genetic investigation and counseling prior to intracytoplasmic sperm injections].
Lakartidningen - 15 Mar 2000
Mikkelsen A L, Lidegaard O, Meldgaard M, Brøndum-Nielsen K, Lindenberg S
Abstract excerpt
Intracytoplasmatic sperm injection (ICSI) has improved the success rate in treating severe male infertility. The method may now be used with sperm from the epididymis and testis. This article summarizes our knowledge on genetic factors affecting male gamete formation or function. Infertile men with severe impairment of spermatogenesis showed a higher than normal incidence of chromosomal abnormalities and 10-20%...
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